It depends on your objective.
PyQT is distributed under a variety of licenses, and you can basically select the one that fits best for your purpose.
You could select the GPL license, and then run your tool as a service on a server accessible to your customers (SaaS), which does not count as distribution under the terms of GPL. This way you would not therefore need to disclose your own code to your customers.
You could again select the GPL license, distribute your product (including PyQT code) to your customers, and establish a pay-per-use model, where your customers pay you for each trained model they create. In this case you likely have to provide the source code to your customers under the GPL license (and eventually allow your customers to modify the code to by-pass your business model).
You could select the commercial license and distribute your product (including PyQT code) to your customers, and establish a pay-per-use model, where your customers pay you for each trained model they create. In this case you would not have to provide the source code to your customers.
There are many more possible ways for you to implement you business model, the common thing for all of them is that as soon as you distribute the application under GPL you have to provide the source code of your app, and to avoid that you can select the commercial license.